Exenatide once weekly for smoking cessation
نویسندگان
چکیده
منابع مشابه
Exenatide Once Weekly for Smoking Cessation: A Randomized Clinical Trial
Background: Cigarette smoking is the greatest preventable cause of morbidity and premature mortality in the US. Approved pharmacological treatments for smoking cessation are only marginally effective, underscoring the need for improved pharmacotherapies. Glucagon-like peptide-1 (GLP-1) is produced in the intestinal L-cells and in the hindbrain nucleus solitarius. GLP-1 functions to maintain glu...
متن کاملExenatide once weekly in type 2 diabetes.
The difficulties of maintaining long-term glycaemic control with available antidiabetic treatments in patients with type 2 diabetes have led to the need for additional treatments that can replace or be safely combined with existing agents. Patients with type 2 diabetes who have not achieved adequate glucose control at the maximum tolerated doses of their oral therapies have had no alternative o...
متن کاملOnce-Weekly Exenatide Versus Once- or Twice-Daily Insulin Detemir
OBJECTIVE This multicenter, open-label, parallel-arm study compared the efficacy and safety of exenatide once weekly (EQW) with titrated insulin detemir in patients with type 2 diabetes inadequately controlled with metformin (with or without sulfonylureas). RESEARCH DESIGN AND METHODS Patients were randomized to EQW (2 mg) or detemir (once or twice daily, titrated to achieve fasting plasma gl...
متن کاملExenatide once weekly: clinical outcomes and patient satisfaction
BACKGROUND Type 2 diabetes mellitus (T2DM) is a complex disorder in which interactions between environmental and genetic factors result in the development of insulin resistance (in most cases) and progressive pancreatic β-cell failure. The currently available oral anti-diabetes treatments are effective as monotherapy; however, due to the progressive decline in β-cell function, most patients wil...
متن کاملCircaseptan (weekly) rhythms in smoking cessation considerations.
Circaseptan (Weekly) Rhythms in Smoking Cessation Considerations Smokers’ rhythms in contemplating quitting or making quit attempts are poorly understood. Tobacco control has focused on annual events (eg, New Year’s Day), but circaseptan (weekly) time cycles may likewise exist. For example, many illnesses such as strokes are more common on Mondays.1 Do cessation behaviors also have weekly rhythms?
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ژورنال
عنوان ژورنال: Medicine
سال: 2018
ISSN: 0025-7974
DOI: 10.1097/md.0000000000009567